Chirality in chemistry

1. What does it mean for a molecule to be chiral?

A) It has a linear structure.
B) It cannot be superimposed on its mirror image.
C) It has no optical rotation.
D) It has no stereocenters.

2. What is a stereocenter?

A) An atom that is bonded to two groups.
B) An atom that is bonded to four identical groups.
C) An atom that is bonded to four different groups.
D) An atom that is bonded to three different groups.

3. How many stereoisomers can a chiral molecule with one stereocenter have?

A) 2
B) 1
C) 3
D) 4

4. What is a racemic mixture?

A) A 50:50 mixture of two enantiomers.
B) A mixture of structurally different molecules.
C) A mixture of diastereomers.
D) A mixture of meso compounds.

5. Why are enantiomers important in drug development?

A) They can have different biological effects.
B) They have no medicinal value.
C) They are easier to synthesize.
D) They have the same properties in the body.

6. How can chirality be determined experimentally?

A) By checking the molecular weight of a compound.
B) By analyzing the color of the substance.
C) By measuring optical activity with a polarimeter.
D) By counting the number of carbons in a molecule.

7. Which type of light is used in optical rotation experiments?

A) Ultraviolet light.
B) Visible light.
C) Plane-polarized light.
D) Infrared light.

8. What is an optically active compound?

A) A compound that absorbs light.
B) A compound with no stereocenters.
C) A compound with high molecular weight.
D) A compound that rotates the plane of polarized light.

9. How does chirality affect the physical properties of a molecule?

A) Racemic mixtures have higher melting points than pure enantiomers.
B) Enantiomers have identical physical properties except for optical activity.
C) Chiral molecules are always more soluble than achiral molecules.
D) Diastereomers have identical boiling points.

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